MolNFT v1 · #75093 · protein

MAP kinase LMAMPK10 from leishmania major (1.95 angs resolution)

3PG1 · Mitogen-activated protein kinase, putative (MAP kinase-like…: “MAP kinase LMAMPK10 from leishmania major (1.95 angs resolution)”. X-ray diffraction, 4 pockets (best druggability 0.61). MolNFT v1 #75093 on GenesisL1: 3D structure…

PDB: 3PG1
Type: protein
Length: 341 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Mitogen-activated protein kinase, putative (MAP kinase-like protein)
UniProt: Q4QHJ8
Pockets: 4 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Mitogen-activated protein kinase, putative (MAP kinase-like protein)	protein	341	45% helix, 14% strand	Q4QHJ8

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	306	0.61	0.78	39	empty
2	141	0.50	0.79	20	empty
3	64	0.28	0.73	19	empty
4	55	0.25	0.72	16	empty

Compared structures

3PG1 · MAP kinase LmaMPK10 from Leishmania major (1.95 angs resolution) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4QHJ8
Elsewhere: RCSB PDB 3PG1 · PDBe 3PG1 · UniProt Q4QHJ8

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.