MolNFT v1 · #75085 · protein

Crystal structure of untagged C54A mutant flavin reductase (dszd) in complex with FMN from mycobacterium goodii

3PFT: “Crystal structure of untagged C54A mutant flavin reductase (dszd) in complex with FMN from mycobacterium…”. X-ray diffraction, 1 ligand (FMN), 2 pockets (best druggability 0.68). MolNFT v1 #75085 on GenesisL1: 3D structure, binding…

PDB: 3PFT
Type: protein
Length: 313 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Flavin reductase
EC: 1.5.1.29
UniProt: B6CDL6
Ligands: FMN
Pockets: 2 · best druggability 0.68

Structure

x-ray diffraction · 2 distinct chains · 12% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Flavin reductase (EC 1.5.1.29)	protein	156	13% helix, 48% strand	B6CDL6
B	Flavin reductase (EC 1.5.1.29)	protein	157	11% helix, 46% strand	B6CDL6

Ligands and binding sites

FMN · Flavin mononucleotide · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	489	0.68	0.79	43	FMN
2	462	0.67	0.79	43	FMN

Interfaces

1 interface between chains.

A–B · 2480 Å² buried · 19 hydrogen bonds · protein-protein

Compared structures

3PFT · Crystal Structure of Untagged C54A Mutant Flavin Reductase (DszD) in Complex with FMN… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B6CDL6
Elsewhere: RCSB PDB 3PFT · PDBe 3PFT · UniProt B6CDL6

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