Research workbench

Crystal structure of untagged C54A mutant flavin reductase (dszd) in complex with FMN from mycobacterium goodii

Analyse Crystal structure of untagged C54A mutant flavin reductase (dszd) in complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3PFT
Type: protein
Length: 313 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Flavin reductase
EC: 1.5.1.29
UniProt: B6CDL6
Ligands: FMN
Pockets: 2 · best druggability 0.68

Structure

x-ray diffraction · 2 distinct chains · 12% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Flavin reductase (EC 1.5.1.29)	protein	156	13% helix, 48% strand	B6CDL6
B	Flavin reductase (EC 1.5.1.29)	protein	157	11% helix, 46% strand	B6CDL6

Ligands and binding sites

FMN · Flavin mononucleotide · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	489	0.68	0.79	43	FMN
2	462	0.67	0.79	43	FMN

Interfaces

1 interface between chains.

A–B · 2480 Å² buried · 19 hydrogen bonds · protein-protein

Compared structures

3PFT · Crystal Structure of Untagged C54A Mutant Flavin Reductase (DszD) in Complex with FMN… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B6CDL6
Elsewhere: RCSB PDB 3PFT · PDBe 3PFT · UniProt B6CDL6

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.