MolNFT v1 · #74850 · protein
Crystal structure of single chain recombinant jacalin showing highly dynamic posttranslational excission loop that reduces binding affinity
3P8S: “Crystal structure of single chain recombinant jacalin showing highly dynamic posttranslational excission loop…”. X-ray diffraction, 2 pockets (best druggability 0.39). MolNFT v1 #74850 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3P8S
- Type
- protein
- Length
- 302 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Jacalin
- UniProt
- Q38723
- Pockets
- 2 · best druggability 0.39
Structure
x-ray diffraction · 2 distinct chains · 0% helix, 64% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Jacalin | protein | 150 | 0% helix, 64% strand | Q38723 |
| B | Jacalin | protein | 152 | 0% helix, 64% strand | Q38723 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 124 | 0.39 | 0.74 | 25 | empty |
| 2 | 90 | 0.33 | 0.74 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 974 Ų buried · 22 hydrogen bonds · protein-protein
Compared structures
- 3P8S · Crystal structure of single chain recombinant jacalin showing highly dynamic… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q38723
- Elsewhere: RCSB PDB 3P8S · PDBe 3P8S · UniProt Q38723
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