MolNFT v1 · #74567 · protein
Human steroidogenic acute regulatory protein
3P0L · Steroidogenic acute regulatory protein, mitochondrial: “Human steroidogenic acute regulatory protein”. X-ray diffraction, 15 pockets (best druggability 0.79). MolNFT v1 #74567 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 3P0L
- Type
- protein
- Length
- 808 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Steroidogenic acute regulatory protein, mitochondrial
- UniProt
- P49675
- Pockets
- 15 · best druggability 0.79
Structure
x-ray diffraction · 4 distinct chains · 27% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Steroidogenic acute regulatory protein, mitochondrial | protein | 210 | 27% helix, 36% strand | P49675 |
| B | Steroidogenic acute regulatory protein, mitochondrial | protein | 208 | 27% helix, 36% strand | P49675 |
| C | Steroidogenic acute regulatory protein, mitochondrial | protein | 205 | 28% helix, 36% strand | P49675 |
| D | Steroidogenic acute regulatory protein, mitochondrial | protein | 185 | 25% helix, 38% strand | P49675 |
Pockets
15 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 305 | 0.79 | 0.90 | 39 | empty |
| 2 | 298 | 0.79 | 0.90 | 37 | empty |
| 3 | 294 | 0.77 | 0.89 | 36 | empty |
| 4 | 249 | 0.71 | 0.86 | 37 | empty |
| 5 | 488 | 0.69 | 0.79 | 59 | empty |
Interfaces
4 interfaces between chains.
- A–B · 394 Ų buried · 8 hydrogen bonds · protein-protein
- B–D · 305 Ų buried · 3 hydrogen bonds · protein-protein
- A–C · 291 Ų buried · 1 hydrogen bond · protein-protein
- A–D · 236 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49675
- Elsewhere: RCSB PDB 3P0L · PDBe 3P0L · UniProt P49675
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