UniProt P49675
14-3-3 protein sigma,Steroidogenic acute regulatory protein, mitochondrial (P49675)
14-3-3 protein sigma,Steroidogenic acute regulatory protein, mitochondrial (UniProt P49675): 7 experimental structures on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P49675
- Protein
- 14-3-3 protein sigma,Steroidogenic acute regulatory protein, mitochondrial
- Experimental structures
- 7
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 4 · 1 record with a druggable one
Structures
7 records of P49675 in the MolNFT archive: 7 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3P0L | Human steroidogenic acute regulatory protein | x-ray diffraction | A, B, C, D | — | — |
| 3P0L | Human steroidogenic acute regulatory protein | x-ray diffraction | A, B, C, D | — | — |
| 5OMA | CH3 chimera of human 14-3-3 sigma with the StARD1 peptide including Ser57 | x-ray diffraction | A, B, C, D | PO4, SO4 | — |
| 5OMA | CH3 chimera of human 14-3-3 sigma with the STARD1 peptide including SER57 | x-ray diffraction | A, B, C, D | PO4, SO4 | — |
| 6T5H | Human 14-3-3 sigma fused to the StARD1 peptide including phosphoserine-57 | x-ray diffraction | A, B | — | 4 (best 0.54) |
| 6T5H | Human 14-3-3 sigma fused to the STARD1 peptide including phosphoserine-57 | x-ray diffraction | A, B | — | — |
| P49675 | AlphaFold monomer V2.0 prediction for steroidogenic acute regulatory protein, mitochondrial (P49675) | — | — | — |
Ligands
Experiment against prediction
- 5OMA chain C against the predicted model P31947: TM-score 0.98, RMSD 0.86 Å
- 5OMA chain C against the predicted model P31947: TM-score 0.98, RMSD 0.86 Å
- 5OMA chain A against the predicted model P31947: TM-score 0.96, RMSD 1.33 Å
- 5OMA chain A against the predicted model P31947: TM-score 0.96, RMSD 1.33 Å
- 5OMA chain B against the predicted model P31947: TM-score 0.96, RMSD 1.36 Å
- 5OMA chain B against the predicted model P31947: TM-score 0.96, RMSD 1.36 Å
- 6T5H chain A against the predicted model P31947: TM-score 0.95, RMSD 1.13 Å
- 6T5H chain A against the predicted model P31947: TM-score 0.95, RMSD 1.13 Å
- 6T5H chain B against the predicted model P31947: TM-score 0.94, RMSD 1.17 Å
- 6T5H chain B against the predicted model P31947: TM-score 0.94, RMSD 1.17 Å
Elsewhere
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