Crystal structure of a geranylgeranyl bacteriochlorophyll reductase- like (TA0516) from thermoplasma acidophilum at 1.60 a resolution

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 29% strand (DSSP).

Ligands and binding sites

• FAD · Flavin-adenine dinucleotide · ligand · chains A
• OZ2 · (2R)-3-{[(R)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-2-[(6Z)-tridec-6-enoyloxy]propyl (9Z)-octadec-9-enoate · ligand · chains A
• EDO · 1,2-ethanediol · additive · 11 copies · chains A
• GOL · Glycerol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 12 modified (engineered).

Compared structures

• 3OZ2 · Crystal structure of a geranylgeranyl bacteriochlorophyll reductase-like (Ta0516) from… · the same entry in another collection · chain A against A, TM-score 1.00
• Q9HKS9 · AlphaFold monomer V2.0 prediction for digeranylgeranylglycerophospholipid reductase… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9HKS9
• Elsewhere: RCSB PDB 3OZ2 · PDBe 3OZ2 · UniProt Q9HKS9