MolNFT v1 · #7450 · protein + RNA

Complex of HIV-1 rre-iib RNA with rsg-1.2 peptide

1G70 · HIV-1 rre-iib 32 nucleotide RNA: “Complex of HIV-1 rre-iib RNA with rsg-1.2 peptide”. Solution nmr, 1 pocket (best druggability 0.43). MolNFT v1 #7450 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1G70
Type: protein + RNA
Length: 48 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: HIV-1 rre-iib 32 nucleotide RNA; Rsg-1.2 peptide
UniProt: Q7SIF5
Pockets: 1 · best druggability 0.43

Structure

solution nmr · 2 distinct chains · 63% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	HIV-1 rre-iib 32 nucleotide RNA	rna	32	—	—
B	Rsg-1.2 peptide	protein	16	63% helix, 0% strand	Q7SIF5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.43	0.84	12	empty

Interfaces

1 interface between chains.

A–B · 933 Å² buried · 25 hydrogen bonds · protein-nucleic

Compared structures

1G70 · Complex of HIV-1 rre-iib RNA with rsg-1.2 peptide · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7SIF5
Elsewhere: RCSB PDB 1G70 · PDBe 1G70 · UniProt Q7SIF5

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