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Complex of HIV-1 rre-iib RNA with rsg-1.2 peptide

Analyse Complex of HIV-1 rre-iib RNA with rsg-1.2 peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1G70
Type
protein + RNA
Length
48 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
HIV-1 rre-iib 32 nucleotide RNA; Rsg-1.2 peptide
UniProt
Q7SIF5
Pockets
1 · best druggability 0.43

Structure

solution nmr · 2 distinct chains · 63% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AHIV-1 rre-iib 32 nucleotide RNArna32——
BRsg-1.2 peptideprotein1663% helix, 0% strandQ7SIF5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1520.430.8412empty

Interfaces

1 interface between chains.

  • A–B · 933 Ų buried · 25 hydrogen bonds · protein-nucleic

Compared structures

  • 1G70 · Complex of HIV-1 rre-iib RNA with rsg-1.2 peptide · the same entry in another collection · chain A against A, TM-score 1.00

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