MolNFT v1 · #73967 · protein
Crystal structure of yeast telomere protein CDC13 OB1 and the catalytic subunit of DNA polymerase alpha POL1
3OIQ · Cell division control protein 13: “Crystal structure of yeast telomere protein CDC13 OB1 and the catalytic subunit of DNA polymerase alpha POL1”. X-ray diffraction, 3 pockets (best druggability 0.35). MolNFT v1 #73967 on GenesisL1…
- PDB
- 3OIQ
- Type
- protein
- Length
- 213 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cell division control protein 13; DNA polymerase alpha catalytic subunit a
- UniProt
- P32797, P13382
- Pockets
- 3 · best druggability 0.35
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cell division control protein 13 | protein | 183 | 37% helix, 30% strand | P32797 |
| B | DNA polymerase alpha catalytic subunit a | protein | 30 | 77% helix, 3% strand | P13382 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 107 | 0.35 | 0.73 | 17 | empty |
| 2 | 66 | 0.35 | 0.77 | 16 | empty |
| 3 | 55 | 0.29 | 0.75 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 722 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 3OIQ · Crystal structure of yeast telomere protein Cdc13 OB1 and the catalytic subunit of DNA… · the same entry in another collection · chain A against A, TM-score 1.00
- P32797 · AlphaFold monomer V2.0 prediction for cell division control protein 13 (P32797) · a predicted model of the same protein · chain A against A, TM-score 0.98
- P13382 · AlphaFold monomer V2.0 prediction for DNA polymerase alpha catalytic subunit a (P13382) · a predicted model of the same protein · chain B against A, TM-score 0.71
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P32797
- Every structure of UniProt P13382
- Elsewhere: RCSB PDB 3OIQ · PDBe 3OIQ · UniProt P32797 · UniProt P13382
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