MolNFT v1 · #7378 · protein
Crystal structure of the salmonella tyrosine phosphatase and GTPase activating protein sptp
1G4W · Protein tyrosine phosphatase sptp: “Crystal structure of the salmonella tyrosine phosphatase and GTPase activating protein sptp”. X-ray diffraction, 4 pockets (best druggability 0.58). MolNFT v1 #7378 on GenesisL1: 3D structure…
- PDB
- 1G4W
- Type
- protein
- Length
- 341 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein tyrosine phosphatase sptp
- UniProt
- P74873
- Pockets
- 4 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| R | Protein tyrosine phosphatase sptp | protein | 341 | 43% helix, 16% strand | P74873 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 244 | 0.58 | 0.79 | 27 | empty |
| 2 | 236 | 0.52 | 0.76 | 24 | empty |
| 3 | 56 | 0.38 | 0.81 | 16 | empty |
| 4 | 52 | 0.26 | 0.74 | 15 | empty |
Compared structures
- 1G4W · Crystal structure of the salmonella tyrosine phosphatase and GTPase activating protein… · the same entry in another collection · chain R against R, TM-score 1.00
- P74873 · AlphaFold monomer V2.0 prediction for secreted effector protein sptp (P74873) · a predicted model of the same protein · chain R against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P74873
- Elsewhere: RCSB PDB 1G4W · PDBe 1G4W · UniProt P74873
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.