MolNFT v1 · #7314 · protein
Hnf-1ALPHA dimerization domain, with selenomethionine substitued at leu 12
1G2Y · Hepatocyte nuclear factor 1-alpha: “Hnf-1ALPHA dimerization domain, with selenomethionine substitued at leu 12”. X-ray diffraction. MolNFT v1 #7314 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1G2Y
- Type
- protein
- Length
- 120 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hepatocyte nuclear factor 1-alpha
- UniProt
- P22361
Structure
x-ray diffraction · 3 distinct chains · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hepatocyte nuclear factor 1-alpha | protein | 31 | 74% helix, 0% strand | P22361 |
| B, D | Hepatocyte nuclear factor 1-alpha | protein | 30 | 73% helix, 0% strand | P22361 |
| C | Hepatocyte nuclear factor 1-alpha | protein | 29 | 79% helix, 0% strand | P22361 |
Interfaces
6 interfaces between chains.
- B–D · 714 Ų buried · 4 hydrogen bonds · protein-protein
- A–C · 682 Ų buried · 4 hydrogen bonds · protein-protein
- A–B · 439 Ų buried · 2 hydrogen bonds · protein-protein
- C–D · 360 Ų buried · 1 hydrogen bond · protein-protein
- B–C · 208 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 1G2Y · Hnf-1ALPHA dimerization domain, with selenomethionine substitued at leu 12 · the same entry in another collection · chain A against A, TM-score 1.00
- P22361 · AlphaFold monomer V2.0 prediction for hepatocyte nuclear factor 1-alpha (P22361) · a predicted model of the same protein · chain A against A, TM-score 0.71
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22361
- Elsewhere: RCSB PDB 1G2Y · PDBe 1G2Y · UniProt P22361
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