MolNFT v1 · #7303 · protein
Crystal structure of the ligand binding domain of the ultraspiracle protein usp, the ortholog of rxrs in insects
1G2N: “Crystal structure of the ligand binding domain of the ultraspiracle protein usp, the ortholog of rxrs in…”. X-ray diffraction, 1 ligand (EPH), 3 pockets (best druggability 0.83). MolNFT v1 #7303 on GenesisL1: 3D structure, binding…
- PDB
- 1G2N
- Type
- protein
- Length
- 246 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ultraspiracle protein
- UniProt
- Q7SIF6
- Ligands
- EPH
- Pockets
- 3 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 64% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ultraspiracle protein | protein | 246 | 64% helix, 4% strand | Q7SIF6 |
Ligands and binding sites
- EPH · L-alpha-phosphatidyl-beta-oleoyl-gamma-palmitoyl-phosphatidylethanolamine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 516 | 0.83 | 0.89 | 35 | EPH |
| 2 | 266 | 0.56 | 0.77 | 26 | empty |
| 3 | 124 | 0.42 | 0.76 | 25 | empty |
Compared structures
- 1G2N · Crystal structure of the ligand binding domain of the ultraspiracle protein usp, the… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7SIF6
- Elsewhere: RCSB PDB 1G2N · PDBe 1G2N · UniProt Q7SIF6
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