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MolNFT v1 · #7241 · protein

Crystal structure of the ligand binding domain of lir-1 (ILT2)

1G0X · Leucocyte immunoglobulin-like receptor-1: “Crystal structure of the ligand binding domain of lir-1 (ILT2)”. X-ray diffraction, 1 pocket (best druggability 0.33). MolNFT v1 #7241 on GenesisL1: 3D structure, binding sites and pockets…

PDB
1G0X
Type
protein
Length
192 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Leucocyte immunoglobulin-like receptor-1
UniProt
Q8NHL6
Pockets
1 · best druggability 0.33

Structure

x-ray diffraction · 1 distinct chain · 7% helix, 45% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ALeucocyte immunoglobulin-like receptor-1protein1927% helix, 45% strandQ8NHL6

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1840.330.7423empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

  • 1G0X · Crystal structure of the ligand binding domain of lir-1 (ILT2) · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8NHL6 · AlphaFold monomer V2.0 prediction for leukocyte immunoglobulin-like receptor subfamily B… · a predicted model of the same protein · chain A against A, TM-score 0.92

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