MolNFT v1 · #72261 · protein

Erythrina corallodendron lectin mutant (Y106G) with N- acetylgalactosamine

3N35: “Erythrina corallodendron lectin mutant (Y106G) with N- acetylgalactosamine”. X-ray diffraction, 3 ligands (A2G, MN, CA), 1 pocket (best druggability 0.35). MolNFT v1 #72261 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 3N35
Type: protein
Length: 242 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lectin
UniProt: P16404
Ligands: A2G, MN, CA
Pockets: 1 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 4% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lectin	protein	242	4% helix, 45% strand	P16404

Ligands and binding sites

A2G · 2-acetamido-2-deoxy-alpha-D-galactopyranose · sugar · chains A
MN · Manganese (II) ion · metal · chains A
CA · Calcium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	57	0.35	0.79	16	empty

Compared structures

3N35 · Erythrina corallodendron lectin mutant (Y106G) with N-Acetylgalactosamine · the same entry in another collection · chain A against A, TM-score 1.00
P16404 · AlphaFold monomer V2.0 prediction for lectin (P16404) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P16404
Elsewhere: RCSB PDB 3N35 · PDBe 3N35 · UniProt P16404

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