MolNFT v1 · #72229 · protein
Molecular basis of the inhibition of henipa viruses
3N27 · Fusion glycoprotein F0, linker, fusion glycoprotein F0: “Molecular basis of the inhibition of henipa viruses”. X-ray diffraction, 1 pocket (best druggability 0.72). MolNFT v1 #72229 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3N27
- Type
- protein
- Length
- 222 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fusion glycoprotein F0, linker, fusion glycoprotein F0
- UniProt
- Q9IH63
- Pockets
- 1 · best druggability 0.72
Structure
x-ray diffraction · 3 distinct chains · 89% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fusion glycoprotein F0, linker, fusion glycoprotein F0 | protein | 73 | 88% helix, 0% strand | Q9IH63 |
| B | Fusion glycoprotein F0, linker, fusion glycoprotein F0 | protein | 79 | 87% helix, 0% strand | Q9IH63 |
| C | Fusion glycoprotein F0, linker, fusion glycoprotein F0 | protein | 70 | 91% helix, 0% strand | Q9IH63 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 56 | 0.72 | 0.98 | 14 | TBU |
Interfaces
3 interfaces between chains.
- A–B · 1298 Ų buried · 10 hydrogen bonds · protein-protein
- A–C · 1293 Ų buried · 7 hydrogen bonds · protein-protein
- B–C · 1274 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 3N27 · Molecular Basis of the Inhibition of Henipa Viruses · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9IH63
- Elsewhere: RCSB PDB 3N27 · PDBe 3N27 · UniProt Q9IH63
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