MolNFT v1 · #71934 · protein
Glycogen phosphorylase complexed with 4-nitrobenzaldehyde-4-(beta-D- glucopyranosyl)-thiosemicarbazone
3MT9 · Glycogen phosphorylase, muscle form: “Glycogen phosphorylase complexed with 4-nitrobenzaldehyde-4-(beta-D- glucopyranosyl)-thiosemicarbazone”. X-ray diffraction, 1 ligand (18O), 14 pockets (best druggability 0.81). MolNFT v1 #71934…
- PDB
- 3MT9
- Type
- protein
- Length
- 810 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycogen phosphorylase, muscle form
- EC
- 2.4.1.1
- UniProt
- P00489
- Ligands
- 18O
- Pockets
- 14 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 53% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glycogen phosphorylase, muscle form (EC 2.4.1.1) | protein | 810 | 53% helix, 15% strand | P00489 |
Ligands and binding sites
- 18O · N-({(2E)-2-[(4-nitrophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine · ligand · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
14 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 174 | 0.81 | 0.96 | 37 | 18O |
| 2 | 82 | 0.73 | 0.96 | 26 | empty |
| 3 | 458 | 0.69 | 0.80 | 60 | empty |
| 4 | 117 | 0.52 | 0.81 | 19 | empty |
| 5 | 224 | 0.52 | 0.76 | 22 | empty |
Modifications
Observed in the structure: 1 modified (cofactor).
Compared structures
- 3MT9 · Glycogen phosphorylase complexed with 4-nitrobenzaldehyde-4-(beta-D-glucopyranosyl)-thiose… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00489
- Elsewhere: RCSB PDB 3MT9 · PDBe 3MT9 · UniProt P00489
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.