MolNFT v1 · #71427 · protein
Structure of the E. COLI chaperone papd in complex with the pilin domain of the papgii adhesin
3ME0 · Chaperone protein papd: “Structure of the E. COLI chaperone papd in complex with the pilin domain of the papgii adhesin”. X-ray diffraction, 3 pockets (best druggability 0.51). MolNFT v1 #71427 on GenesisL1: 3D structure, binding…
- PDB
- 3ME0
- Type
- protein
- Length
- 344 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chaperone protein papd; Papg protein
- UniProt
- P15319, Q8FDY8
- Pockets
- 3 · best druggability 0.51
Structure
x-ray diffraction · 2 distinct chains · 5% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chaperone protein papd | protein | 216 | 8% helix, 51% strand | P15319 |
| B | Papg protein | protein | 128 | 0% helix, 52% strand | Q8FDY8 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 233 | 0.51 | 0.75 | 30 | empty |
| 2 | 95 | 0.35 | 0.74 | 18 | empty |
| 3 | 63 | 0.28 | 0.74 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1904 Ų buried · 31 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 modified, 2 disulfide (engineered, disulfide).
Compared structures
- 3ME0 · Structure of the E. coli chaperone PAPD in complex with the pilin domain of the PapGII… · the same entry in another collection · chain A against A, TM-score 1.00
- P15319 · AlphaFold monomer V2.0 prediction for chaperone protein papd (P15319) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15319
- Every structure of UniProt Q8FDY8
- Elsewhere: RCSB PDB 3ME0 · PDBe 3ME0 · UniProt P15319 · UniProt Q8FDY8
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