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MolNFT v1 · #71397 · protein

Crystal structure of the first two rrm domains of yeast POLY(U) binding protein (PUB1)

3MD3 · Nuclear and cytoplasmic polyadenylated RNA-binding protein…: “Crystal structure of the first two rrm domains of yeast POLY(U) binding protein (PUB1)”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.36). MolNFT v1…

PDB
3MD3
Type
protein
Length
165 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1
UniProt
P32588
Ligands
SO4
Pockets
1 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 25% helix, 38% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANuclear and cytoplasmic polyadenylated RNA-binding protein PUB1protein16525% helix, 38% strandP32588

Ligands and binding sites

  • SO4 · Sulfate ion · ion · 8 copies · chains A
  • GOL · Glycerol · additive · 8 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1800.360.7617empty

Compared structures

  • 3MD3 · Crystal Structure of the First Two RRM Domains of Yeast Poly(U) Binding Protein (Pub1) · the same entry in another collection · chain A against A, TM-score 1.00
  • P32588 · AlphaFold monomer V2.0 prediction for nuclear and cytoplasmic polyadenylated RNA-binding… · a predicted model of the same protein · chain A against A, TM-score 0.61

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