MolNFT v1 · #71240 · protein

Structure of tubz-GTP-G-S

3M89 · FTSZ/TUBULIN-related protein: “Structure of tubz-GTP-G-S”. X-ray diffraction, 1 ligand (GSP), 4 pockets (best druggability 0.56). MolNFT v1 #71240 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3M89
Type: protein
Length: 393 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: FTSZ/TUBULIN-related protein
UniProt: Q8KNP3
Ligands: GSP
Pockets: 4 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	FTSZ/TUBULIN-related protein	protein	393	45% helix, 19% strand	Q8KNP3

Ligands and binding sites

GSP · 5'-guanosine-diphosphate-monothiophosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	271	0.56	0.77	34	empty
2	118	0.53	0.82	20	empty
3	140	0.48	0.78	30	GSP
4	53	0.28	0.74	15	empty

Modifications

Observed in the structure: 9 modified (engineered).

Compared structures

3M89 · Structure of TubZ-GTP-g-S · the same entry in another collection · chain A against A, TM-score 1.00
Q8KNP3 · AlphaFold monomer V2.0 prediction for tubulin-like protein tubz (Q8KNP3) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8KNP3
Elsewhere: RCSB PDB 3M89 · PDBe 3M89 · UniProt Q8KNP3

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