GL1X · GenesisL1 explorer

MolNFT v1 · #70935 · protein

EGFR kinase domain complexed with an IMIDAZO[2,1-B]THIAZOLE inhibitor

3LZB: “EGFR kinase domain complexed with an IMIDAZO[2,1-B]THIAZOLE inhibitor”. X-ray diffraction. MolNFT v1 #70935 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
3LZB
Type
protein
Length
1,082 residues
Chains
8
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P00533

Structure

x-ray diffraction · 5 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B—protein265—P00533
C—protein259—P00533
D—protein261—P00533
E, H—protein9—P00533
F, G—protein7—P00533

Compared structures

  • 3LZB · EGFR kinase domain complexed with an imidazo[2,1-b]thiazole inhibitor · the same entry in another collection · chain H against H, TM-score 1.00
  • P00533 · AlphaFold monomer V2.0 prediction for epidermal growth factor receptor (P00533) · a predicted model of the same protein · chain D against A, TM-score 0.95

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