MolNFT v1 · #70893 · protein

Crystal structure of fluorophore-labeled class a beta-lactamase penp

3LY3: “Crystal structure of fluorophore-labeled class a beta-lactamase penp”. X-ray diffraction, 2 pockets (best druggability 0.60). MolNFT v1 #70893 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3LY3
Type: protein
Length: 259 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-lactamase
EC: 3.5.2.6
UniProt: P00808
Pockets: 2 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-lactamase (EC 3.5.2.6)	protein	259	43% helix, 18% strand	P00808

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	174	0.60	0.83	38	empty
2	99	0.53	0.83	19	empty

Compared structures

3LY3 · Crystal Structure of fluorophore-labeled Class A Beta-lactamase PenP · the same entry in another collection · chain A against A, TM-score 1.00
P00808 · AlphaFold monomer V2.0 prediction for beta-lactamase (P00808) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00808
Elsewhere: RCSB PDB 3LY3 · PDBe 3LY3 · UniProt P00808

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