MolNFT v1 · #70860 · protein

Crystal structure of mgmppnp-bound nfeob from S. thermophilus

3LX5 · Ferrous iron uptake transporter protein B: “Crystal structure of mgmppnp-bound nfeob from S. thermophilus”. X-ray diffraction, 2 ligands (AGO, MG), 1 pocket (best druggability 0.55). MolNFT v1 #70860 on GenesisL1: 3D structure…

PDB: 3LX5
Type: protein
Length: 259 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ferrous iron uptake transporter protein B
UniProt: Q5M586
Ligands: AGO, MG
Pockets: 1 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 51% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ferrous iron uptake transporter protein B	protein	259	51% helix, 14% strand	Q5M586

Ligands and binding sites

AGO · 2-amino-9-(5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]-3-O-{[2-(methylamino)phenyl]carbonyl}-beta-D-erythro-pentofuranosyl-2-ulose)-1,9-dihydro-6H-purin-6-one · ligand · chains A
MG · Magnesium ion · metal · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	97	0.55	0.85	27	AGO, MG

Compared structures

3LX5 · Crystal structure of mGMPPNP-bound NFeoB from S. thermophilus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5M586
Elsewhere: RCSB PDB 3LX5 · PDBe 3LX5 · UniProt Q5M586

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