MolNFT v1 · #70620 · protein
HIV integrase
3LPU: “HIV integrase”. X-ray diffraction, 4 ligands (976, P03, CA). MolNFT v1 #70620 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3LPU
- Type
- protein
- Length
- 144 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Integrase
- UniProt
- Q76353
- Ligands
- 976, P03, CA, SO4
Structure
x-ray diffraction · 1 distinct chain · 49% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Integrase | protein | 144 | 49% helix, 22% strand | Q76353 |
Ligands and binding sites
- 976 · (2S)-2-(6-chloro-2-methyl-4-phenylquinolin-3-yl)pentanoic acid · ligand · chains A
- P03 · 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol · ligand · chains A
- CA · Calcium ion · metal · chains A
- SO4 · Sulfate ion · ion · 3 copies · chains A
- PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 2 modified (nonstandard).
Compared structures
- 3LPU · HIV integrase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q76353
- Elsewhere: RCSB PDB 3LPU · PDBe 3LPU · UniProt Q76353
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