MolNFT v1 · #70600 · protein
Crystal structure of a subtilisin-like protease
3LPA · Acidic extracellular subtilisin-like protease APRV2: “Crystal structure of a subtilisin-like protease”. X-ray diffraction, 1 ligand (CA), 1 pocket (best druggability 0.48). MolNFT v1 #70600 on GenesisL1: 3D structure, binding sites…
- PDB
- 3LPA
- Type
- protein
- Length
- 340 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Acidic extracellular subtilisin-like protease APRV2
- EC
- 3.4.21.-
- UniProt
- A5EXI3
- Ligands
- CA
- Pockets
- 1 · best druggability 0.48
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Acidic extracellular subtilisin-like protease APRV2 (EC 3.4.21.-) | protein | 340 | 29% helix, 18% strand | A5EXI3 |
Ligands and binding sites
- CA · Calcium ion · metal · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 235 | 0.48 | 0.74 | 38 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 3LPA · Crystal structure of a subtilisin-like protease · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5EXI3
- Elsewhere: RCSB PDB 3LPA · PDBe 3LPA · UniProt A5EXI3
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