The crystal structure of the N-terminal domain of a rpir transcriptional regulator from staphylococcus epidermidis to 1.4A

Structure

x-ray diffraction · 2 distinct chains · 63% helix, 2% strand (DSSP).

Ligands and binding sites

• NI · Nickel (II) ion · metal · 2 copies · chains A, B
• NA · Sodium ion · metal · chains A
• CL · Chloride ion · ion · 2 copies · chains A, B
• MXE · 2-methoxyethanol · additive · 2 copies · chains A
• TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · 2 copies · chains B, A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 630 Ų buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

• 3IWF · The Crystal Structure of the N-terminal domain of a RpiR Transcriptional Regulator from… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q8CNB1
• Elsewhere: RCSB PDB 3IWF · PDBe 3IWF · UniProt Q8CNB1