MolNFT v1 · #67680 · protein
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with NADPH and Q-8 antifolate
3IRO: “Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with NADPH and Q-8 antifolate”. X-ray diffraction. MolNFT v1 #67680 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3IRO
- Type
- protein
- Length
- 2,062 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q27793
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 518 | — | Q27793 |
| B | — | protein | 515 | — | Q27793 |
| C | — | protein | 516 | — | Q27793 |
| D | — | protein | 513 | — | Q27793 |
Compared structures
- 3IRO · Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase complexed with NADPH and… · the same entry in another collection · chain D against D, TM-score 1.00
- Q27793 · AlphaFold monomer V2.0 prediction for bifunctional dihydrofolate reductase-thymidylate… · a predicted model of the same protein · chain D against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q27793
- Elsewhere: RCSB PDB 3IRO · PDBe 3IRO · UniProt Q27793
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