UniProt Q27793
Q27793
Q27793 (UniProt Q27793): 14 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q27793
- Experimental structures
- 14
- Predicted models
- 1
Structures
15 records of Q27793 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2H2Q | Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate synthase | x-ray diffraction | A, B | — | — |
| 2H2Q | Crystal structure of trypanosoma cruzi dihydrofolate reductase- thymidylate synthase | x-ray diffraction | A, B | — | — |
| 3CL9 | Structure of bifunctional TcDHFR-TS in complex with MTX | x-ray diffraction | A | — | — |
| 3CL9 | Structure of bifunctional tcdhfr-ts in complex with mtx | x-ray diffraction | A | — | — |
| 3CLB | Structure of bifunctional TcDHFR-TS in complex with TMQ | x-ray diffraction | A, B, C, D | — | — |
| 3CLB | Structure of bifunctional tcdhfr-ts in complex with tmq | x-ray diffraction | A, B, C, D | — | — |
| 3INV | Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase COMPLEXED WITH NADPH, dUMP AND C-448… | x-ray diffraction | A, B | — | — |
| 3INV | Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with NADPH, dump and C-448… | x-ray diffraction | A, B | — | — |
| 3IRM | Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase COMPLEXED WITH Cycloguanil | x-ray diffraction | A, B, C, D | — | — |
| 3IRM | Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with cycloguanil | x-ray diffraction | A, B, C, D | — | — |
| 3IRN | Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase COMPLEXED WITH NADPH AND Cycloguanil | x-ray diffraction | A, B, C, D | — | — |
| 3IRN | Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with NADPH and cycloguanil | x-ray diffraction | A, B, C, D | — | — |
| 3IRO | Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase complexed with NADPH and Q-8… | x-ray diffraction | A, B, C, D | — | — |
| 3IRO | Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with NADPH and Q-8… | x-ray diffraction | A, B, C, D | — | — |
| Q27793 | AlphaFold monomer V2.0 prediction for bifunctional dihydrofolate reductase-thymidylate synthase… | predicted | A | — | — |
Experiment against prediction
- 3INV chain A against the predicted model Q27793: TM-score 0.99, RMSD 0.99 Å
- 3INV chain A against the predicted model Q27793: TM-score 0.99, RMSD 0.99 Å
- 3INV chain B against the predicted model Q27793: TM-score 0.99, RMSD 1.02 Å
- 3INV chain B against the predicted model Q27793: TM-score 0.99, RMSD 1.02 Å
- 3CLB chain C against the predicted model Q27793: TM-score 0.98, RMSD 1.06 Å
- 3CLB chain C against the predicted model Q27793: TM-score 0.98, RMSD 1.06 Å
- 3CLB chain D against the predicted model Q27793: TM-score 0.98, RMSD 1.06 Å
- 3CLB chain D against the predicted model Q27793: TM-score 0.98, RMSD 1.06 Å
- 3IRM chain D against the predicted model Q27793: TM-score 0.98, RMSD 1.12 Å
- 3IRM chain D against the predicted model Q27793: TM-score 0.98, RMSD 1.12 Å
Elsewhere
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