MolNFT v1 · #67645 · protein
Structure of O-acetylserine sulfhydrylase in complex with peptide mnydi
3IQH · Cysteine synthase: “Structure of O-acetylserine sulfhydrylase in complex with peptide mnydi”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.58). MolNFT v1 #67645 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3IQH
- Type
- protein
- Length
- 313 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cysteine synthase; Mnydi
- EC
- 2.5.1.47
- UniProt
- P45040
- Ligands
- SO4
- Pockets
- 1 · best druggability 0.58
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | Cysteine synthase (EC 2.5.1.47) | protein | 310 | 43% helix, 17% strand | P45040 |
| P | Mnydi | protein | 3 | 0% helix, 0% strand | — |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains X, P
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 263 | 0.58 | 0.78 | 44 | SO4 |
Interfaces
1 interface between chains.
- X–P · 389 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (cofactor).
Compared structures
- 3IQH · Structure of O-Acetylserine Sulfhydrylase in Complex with Peptide MNYDI · the same entry in another collection · chain X against X, TM-score 1.00
- P45040 · AlphaFold monomer V2.0 prediction for cysteine synthase (P45040) · a predicted model of the same protein · chain X against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P45040
- Elsewhere: RCSB PDB 3IQH · PDBe 3IQH · UniProt P45040
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.