MolNFT v1 · #67535 · protein
Crystal structure of the GRB2 SH2 domain in complex with a flexible ac-ptyr-ile-asn-NH2 tripeptide mimic
3IN8 · Growth factor receptor-bound protein 2: “Crystal structure of the GRB2 SH2 domain in complex with a flexible ac-ptyr-ile-asn-NH2 tripeptide mimic”. X-ray diffraction, 1 ligand (FYI). MolNFT v1 #67535 on GenesisL1: 3D structure…
- PDB
- 3IN8
- Type
- protein
- Length
- 101 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Growth factor receptor-bound protein 2
- UniProt
- P62993
- Ligands
- FYI
Structure
x-ray diffraction · 1 distinct chain · 16% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Growth factor receptor-bound protein 2 | protein | 101 | 16% helix, 27% strand | P62993 |
Ligands and binding sites
- FYI · N-{(2S)-4-(methylamino)-4-oxo-2-[4-(phosphonooxy)benzyl]butanoyl}-L-isoleucyl-L-aspartamide · ligand · chains A
- FMT · Formic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 3IN8 · Crystal Structure of the Grb2 SH2 Domain in Complex with a Flexible Ac-pTyr-Ile-Asn-NH2… · the same entry in another collection · chain A against A, TM-score 1.00
- P62993 · AlphaFold monomer V2.0 prediction for growth factor receptor-bound protein 2 (P62993) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62993
- Elsewhere: RCSB PDB 3IN8 · PDBe 3IN8 · UniProt P62993
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