MolNFT v1 · #67493 · protein
Structure of the C-terminal SEC63 unit of yeast BRR2, P212121 form
3IM1 · Pre-mRNA-splicing helicase BRR2: “Structure of the C-terminal SEC63 unit of yeast BRR2, P212121 form”. X-ray diffraction, 3 pockets (best druggability 0.49). MolNFT v1 #67493 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 3IM1
- Type
- protein
- Length
- 325 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pre-mRNA-splicing helicase BRR2
- EC
- 3.6.1.-
- UniProt
- P32639
- Pockets
- 3 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-splicing helicase BRR2 (EC 3.6.1.-) | protein | 325 | 41% helix, 20% strand | P32639 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 205 | 0.49 | 0.75 | 18 | empty |
| 2 | 107 | 0.42 | 0.77 | 21 | empty |
| 3 | 76 | 0.31 | 0.74 | 18 | empty |
Compared structures
- 3IM1 · Structure of the C-terminal Sec63 unit of yeast Brr2, P212121 Form · the same entry in another collection · chain A against A, TM-score 1.00
- P32639 · AlphaFold monomer V2.0 prediction for pre-mRNA-splicing helicase BRR2 (P32639) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P32639
- Elsewhere: RCSB PDB 3IM1 · PDBe 3IM1 · UniProt P32639
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