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MolNFT v1 · #66438 · protein

Crystal structure of phosphotyrosine-binding domain from the human tensin-like C1 domain-containing phosphatase (TENC1)

3HQC: “Crystal structure of phosphotyrosine-binding domain from the human tensin-like C1 domain-containing…”. X-ray diffraction, 1 ligand (SO4). MolNFT v1 #66438 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
3HQC
Type
protein
Length
140 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Tensin-like C1 domain-containing phosphatase
EC
3.1.3.-
UniProt
Q63HR2
Ligands
SO4

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 49% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATensin-like C1 domain-containing phosphatase (EC 3.1.3.-)protein14026% helix, 49% strandQ63HR2

Ligands and binding sites

  • SO4 · Sulfate ion · ion · 3 copies · chains A
  • ACT · Acetate ion · additive · 2 copies · chains A
  • GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 1 modified (engineered).

Compared structures

  • 3HQC · Crystal structure of Phosphotyrosine-binding domain from the Human Tensin-like C1… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q63HR2 · AlphaFold monomer V2.0 prediction for tensin-2 (Q63HR2) · a predicted model of the same protein · chain A against A, TM-score 0.89

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