MolNFT v1 · #469318 · protein
AlphaFold monomer V2.0 prediction for tensin-2 (Q63HR2)
Q63HR2: “AlphaFold monomer V2.0 prediction for tensin-2 (Q63HR2)”. 10 pockets (best druggability 0.63). MolNFT v1 #469318 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q63HR2
- Type
- protein
- Length
- 1,409 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6d550761034d809D2162B175722cf896575846D6
- Molecule
- Tensin-2
- UniProt
- Q63HR2
- Pockets
- 10 · best druggability 0.63
Structure
1 distinct chain · 14% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tensin-2 | protein | 1409 | 14% helix, 14% strand | Q63HR2 |
Pockets
10 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 623 | 0.63 | 0.74 | 50 | empty |
| 2 | 282 | 0.57 | 0.77 | 35 | empty |
| 3 | 205 | 0.48 | 0.74 | 18 | empty |
| 4 | 226 | 0.45 | 0.73 | 25 | empty |
| 5 | 109 | 0.43 | 0.77 | 16 | empty |
Compared structures
- 2LOZ · The novel binding mode of DLC1 and Tensin2 PTB domain · an experimental structure of the same protein · chain A against A, TM-score 0.10
- 2LOZ · The novel binding mode of DLC1 and TENSIN2 ptb domain · an experimental structure of the same protein · chain A against A, TM-score 0.10
- 3HQC · Crystal structure of phosphotyrosine-binding domain from the human tensin-like C1… · an experimental structure of the same protein · chain A against A, TM-score 0.10
- 3HQC · Crystal structure of Phosphotyrosine-binding domain from the Human Tensin-like C1… · an experimental structure of the same protein · chain A against A, TM-score 0.10
- 2KNO · NMR Solution Structure of SH2 Domain of the Human Tensin Like C1 Domain Containing… · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 2KNO · NMR solution structure of SH2 domain of the human tensin like C1 domain containing… · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 2L6K · Solution structure of a nonphosphorylated peptide recognizing domain · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 2L6K · Solution Structure of a Nonphosphorylated Peptide Recognizing Domain · an experimental structure of the same protein · chain A against A, TM-score 0.08
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q63HR2
- Elsewhere: UniProt Q63HR2 · AlphaFold DB Q63HR2
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