MolNFT v1 · #6622 · protein

Recombinant human gamma-fibrinogen carboxyl terminal fragment (residues 143-411) bound to calcium at pH 6.0

1FIB: “Recombinant human gamma-fibrinogen carboxyl terminal fragment (residues 143-411) bound to calcium at pH 6.0”. X-ray diffraction, 1 ligand (CA), 1 pocket (best druggability 0.44). MolNFT v1 #6622 on GenesisL1: 3D structure, binding…

PDB: 1FIB
Type: protein
Length: 249 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Gamma-fibrinogen carboxyl terminal fragment
UniProt: P02679
Ligands: CA
Pockets: 1 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 16% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Gamma-fibrinogen carboxyl terminal fragment	protein	249	16% helix, 29% strand	P02679

Ligands and binding sites

CA · Calcium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	116	0.44	0.77	16	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1FIB · Recombinant human gamma-fibrinogen carboxyl terminal fragment (residues 143-411) bound to… · the same entry in another collection · chain A against A, TM-score 1.00
P02679 · AlphaFold monomer V2.0 prediction for fibrinogen gamma chain (P02679) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02679
Elsewhere: RCSB PDB 1FIB · PDBe 1FIB · UniProt P02679

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