MolNFT v1 · #66213 · protein

Crystal structure of serine protease of aeromonas sobria

3HJR · Extracellular serine protease: “Crystal structure of serine protease of aeromonas sobria”. X-ray diffraction, 1 ligand (CA), 5 pockets (best druggability 0.57). MolNFT v1 #66213 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 3HJR
Type: protein
Length: 593 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Extracellular serine protease
EC: 3.4.21.-
UniProt: Q9L5A4
Ligands: CA
Pockets: 5 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 18% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Extracellular serine protease (EC 3.4.21.-)	protein	593	18% helix, 27% strand	Q9L5A4

Ligands and binding sites

CA · Calcium ion · metal · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	192	0.57	0.80	24	empty
2	216	0.46	0.74	35	empty
3	127	0.44	0.77	28	empty
4	91	0.35	0.75	17	empty
5	75	0.34	0.75	12	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

3HJR · Crystal structure of serine protease of Aeromonas sobria · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9L5A4
Elsewhere: RCSB PDB 3HJR · PDBe 3HJR · UniProt Q9L5A4

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