MolNFT v1 · #66198 · protein
Crystal structure of the carboxy-terminal domain of HSP90 from leishmania major, LMJF33.0312
3HJC · Heat shock protein 83-1: “Crystal structure of the carboxy-terminal domain of HSP90 from leishmania major, LMJF33.0312”. X-ray diffraction, 1 ligand (SO4), 7 pockets (best druggability 0.53). MolNFT v1 #66198 on GenesisL1: 3D…
- PDB
- 3HJC
- Type
- protein
- Length
- 387 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heat shock protein 83-1
- UniProt
- Q4Q4I6
- Ligands
- SO4
- Pockets
- 7 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 48% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heat shock protein 83-1 | protein | 387 | 48% helix, 17% strand | Q4Q4I6 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 98 | 0.53 | 0.84 | 24 | empty |
| 2 | 173 | 0.51 | 0.78 | 23 | empty |
| 3 | 74 | 0.41 | 0.79 | 18 | empty |
| 4 | 116 | 0.41 | 0.76 | 16 | empty |
| 5 | 95 | 0.37 | 0.75 | 19 | empty |
Compared structures
- 3HJC · Crystal structure of the carboxy-terminal domain of HSP90 from Leishmania major… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4Q4I6
- Elsewhere: RCSB PDB 3HJC · PDBe 3HJC · UniProt Q4Q4I6
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