MolNFT v1 · #66190 · protein

Minor editosome-associated tutase 1

3HJ4: “Minor editosome-associated tutase 1”. X-ray diffraction, 8 pockets (best druggability 0.77). MolNFT v1 #66190 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3HJ4
Type: protein
Length: 764 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Minor editosome-associated tutase
UniProt: Q4GZ86
Pockets: 8 · best druggability 0.77

Structure

x-ray diffraction · 2 distinct chains · 57% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Minor editosome-associated tutase	protein	381	57% helix, 9% strand	Q4GZ86
B	Minor editosome-associated tutase	protein	383	57% helix, 9% strand	Q4GZ86

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	890	0.77	0.80	76	empty
2	882	0.76	0.79	76	empty
3	466	0.66	0.78	45	empty
4	98	0.41	0.77	17	empty
5	98	0.38	0.76	18	empty

Interfaces

1 interface between chains.

A–B · 648 Å² buried · 7 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 24 modified (engineered).

Compared structures

3HJ4 · Minor Editosome-Associated TUTase 1 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4GZ86
Elsewhere: RCSB PDB 3HJ4 · PDBe 3HJ4 · UniProt Q4GZ86

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