Crystal structure of udp-galactopyranose mutase (oxidized form) in complex with substrate

Structure

x-ray diffraction · 8 distinct chains · 35% helix, 22% strand (DSSP).

Ligands and binding sites

• GDU · Galactose-uridine-5'-diphosphate · ligand · 10 copies · chains A, B, C, D, E, F, G, H, I, J
• FAD · Flavin-adenine dinucleotide · ligand · 10 copies · chains A, B, C, D, E, F, G, H, I, J

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Interfaces

20 interfaces between chains.

• A–I · 1281 Ų buried · 21 hydrogen bonds · protein-protein
• B–H · 1277 Ų buried · 23 hydrogen bonds · protein-protein
• E–G · 1204 Ų buried · 20 hydrogen bonds · protein-protein
• C–F · 1191 Ų buried · 16 hydrogen bonds · protein-protein
• D–J · 1151 Ų buried · 19 hydrogen bonds · protein-protein

Compared structures

• 3HDQ · Crystal structure of UDP-galactopyranose mutase (oxidized form) in complex with substrate · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9RYF1
• Elsewhere: RCSB PDB 3HDQ · PDBe 3HDQ · UniProt Q9RYF1