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MolNFT v1 · #65049 · protein

Crystal structure of polynucleotide phosphorylase (pnpase) core

3GLL · Polyribonucleotide nucleotidyltransferase: “Crystal structure of polynucleotide phosphorylase (pnpase) core”. X-ray diffraction, 4 pockets (best druggability 0.78). MolNFT v1 #65049 on GenesisL1: 3D structure, binding sites and…

PDB
3GLL
Type
protein
Length
494 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Polyribonucleotide nucleotidyltransferase
EC
2.7.7.8
UniProt
A7ZS61
Pockets
4 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APolyribonucleotide nucleotidyltransferase (EC 2.7.7.8)protein49429% helix, 30% strandA7ZS61

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111370.780.80115empty
21560.460.7626empty
3590.350.7817empty
4700.300.7415empty

Compared structures

  • 3GLL · Crystal structure of Polynucleotide Phosphorylase (PNPase) core · the same entry in another collection · chain A against A, TM-score 1.00
  • A7ZS61 · AlphaFold monomer V2.0 prediction for polyribonucleotide nucleotidyltransferase (A7ZS61) · a predicted model of the same protein · chain A against A, TM-score 0.98

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