MolNFT v1 · #304212 · protein
AlphaFold monomer V2.0 prediction for polyribonucleotide nucleotidyltransferase (A7ZS61)
A7ZS61: “AlphaFold monomer V2.0 prediction for polyribonucleotide nucleotidyltransferase (A7ZS61)”. 4 pockets (best druggability 0.75). MolNFT v1 #304212 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A7ZS61
- Type
- protein
- Length
- 711 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7012c0b45c68a2c067644b9d3e5DDa06892c6957
- Molecule
- Polyribonucleotide nucleotidyltransferase
- UniProt
- A7ZS61
- Pockets
- 4 · best druggability 0.75
Structure
1 distinct chain · 35% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Polyribonucleotide nucleotidyltransferase | protein | 711 | 35% helix, 29% strand | A7ZS61 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 890 | 0.75 | 0.79 | 81 | empty |
| 2 | 896 | 0.70 | 0.75 | 85 | empty |
| 3 | 54 | 0.33 | 0.77 | 14 | empty |
| 4 | 64 | 0.29 | 0.74 | 13 | empty |
Compared structures
- 3GCM · Crystal Structure of E. coli polynucleotide phosphorylase bound to RNA and RNase E · an experimental structure of the same protein · chain A against B, TM-score 0.76
- 3GCM · Crystal structure of E. COLI polynucleotide phosphorylase bound to RNA and RNase E · an experimental structure of the same protein · chain A against B, TM-score 0.76
- 3GLL · Crystal structure of polynucleotide phosphorylase (pnpase) core · an experimental structure of the same protein · chain A against A, TM-score 0.69
- 3GLL · Crystal structure of Polynucleotide Phosphorylase (PNPase) core · an experimental structure of the same protein · chain A against A, TM-score 0.69
- 3GME · Crystal structure of polynucleotide phosphorylase in complex with RNase E and manganese · an experimental structure of the same protein · chain A against A, TM-score 0.67
- 3GME · Crystal Structure of Polynucleotide Phosphorylase in complex with RNase E and manganese · an experimental structure of the same protein · chain A against A, TM-score 0.67
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7ZS61
- Elsewhere: UniProt A7ZS61 · AlphaFold DB A7ZS61
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