MolNFT v1 · #64835 · protein

Glutaconyl-CoA decarboxylase a subunit from clostridium symbiosum co- crystallized with glutaconyl-CoA

3GF3 · Glutaconyl-CoA decarboxylase subunit a: “Glutaconyl-CoA decarboxylase a subunit from clostridium symbiosum co- crystallized with glutaconyl-CoA”. X-ray diffraction, 2 ligands (COO, CL), 5 pockets (best druggability 0.56). MolNFT v1…

PDB: 3GF3
Type: protein
Length: 563 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutaconyl-CoA decarboxylase subunit a
EC: 4.1.1.70
UniProt: B7TVP1
Ligands: COO, CL
Pockets: 5 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutaconyl-CoA decarboxylase subunit a (EC 4.1.1.70)	protein	563	43% helix, 18% strand	B7TVP1

Ligands and binding sites

COO · Crotonyl coenzyme A · ligand · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	187	0.56	0.80	40	empty
2	123	0.53	0.82	26	empty
3	109	0.46	0.80	21	empty
4	51	0.36	0.79	21	empty
5	66	0.34	0.76	19	empty

Compared structures

3GF3 · Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B7TVP1
Elsewhere: RCSB PDB 3GF3 · PDBe 3GF3 · UniProt B7TVP1

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