MolNFT v1 · #63833 · protein
Crystal structure of mend from E.COLI
3FLM · 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1…: “Crystal structure of mend from E.COLI”. X-ray diffraction, 10 pockets (best druggability 0.73). MolNFT v1 #63833 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3FLM
- Type
- protein
- Length
- 1,066 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase
- EC
- 2.2.1.9
- UniProt
- P17109
- Pockets
- 10 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 41% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase (EC 2.2.1.9) | protein | 535 | 42% helix, 16% strand | P17109 |
| B | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase (EC 2.2.1.9) | protein | 531 | 40% helix, 16% strand | P17109 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 735 | 0.73 | 0.79 | 93 | empty |
| 2 | 455 | 0.72 | 0.83 | 59 | empty |
| 3 | 599 | 0.68 | 0.77 | 64 | empty |
| 4 | 372 | 0.67 | 0.80 | 49 | empty |
| 5 | 199 | 0.52 | 0.77 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 2622 Ų buried · 45 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P17109
- Elsewhere: RCSB PDB 3FLM · PDBe 3FLM · UniProt P17109
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.