MolNFT v1 · #63827 · protein
The pwwp domain of human DNA (cytosine-5-)-methyltransferase 3 beta
3FLG · DNA (cytosine-5)-methyltransferase 3B: “The pwwp domain of human DNA (cytosine-5-)-methyltransferase 3 beta”. X-ray diffraction, 1 pocket (best druggability 0.31). MolNFT v1 #63827 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3FLG
- Type
- protein
- Length
- 135 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA (cytosine-5)-methyltransferase 3B
- EC
- 2.1.1.37
- UniProt
- Q9UBC3
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) | protein | 135 | 36% helix, 17% strand | Q9UBC3 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.31 | 0.76 | 14 | empty |
Compared structures
- 3FLG · The PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 beta · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UBC3 · AlphaFold monomer V2.0 prediction for DNA (cytosine-5)-methyltransferase 3B (Q9UBC3) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UBC3
- Elsewhere: RCSB PDB 3FLG · PDBe 3FLG · UniProt Q9UBC3
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