MolNFT v1 · #63693 · protein
Crystal structure of the shutoff and exonuclease protein from kaposis sarcoma associated herpesvirus
3FHD · Orf 37: “Crystal structure of the shutoff and exonuclease protein from kaposis sarcoma associated herpesvirus”. X-ray diffraction, 2 ligands (MG, SO4), 4 pockets (best druggability 0.50). MolNFT v1 #63693 on GenesisL1: 3D structure…
- PDB
- 3FHD
- Type
- protein
- Length
- 456 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Orf 37
- UniProt
- P88925
- Ligands
- MG, SO4
- Pockets
- 4 · best druggability 0.50
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Orf 37 | protein | 456 | 43% helix, 18% strand | P88925 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 196 | 0.50 | 0.76 | 32 | empty |
| 2 | 103 | 0.42 | 0.77 | 25 | empty |
| 3 | 133 | 0.42 | 0.76 | 28 | SO4 |
| 4 | 54 | 0.27 | 0.74 | 15 | empty |
Compared structures
- 3FHD · Crystal structure of the Shutoff and Exonuclease Protein from Kaposis Sarcoma Associated… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P88925
- Elsewhere: RCSB PDB 3FHD · PDBe 3FHD · UniProt P88925
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