MolNFT v1 · #63256 · protein
Crystal structure of leut bound to L-alanine and sodium
3F48 · Transporter: “Crystal structure of leut bound to L-alanine and sodium”. X-ray diffraction, 2 ligands (ALA, NA), 4 pockets (best druggability 0.72). MolNFT v1 #63256 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3F48
- Type
- protein
- Length
- 509 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transporter
- UniProt
- O67854
- Ligands
- ALA, NA
- Pockets
- 4 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 78% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transporter | protein | 509 | 78% helix, 1% strand | O67854 |
Ligands and binding sites
- ALA · Alanine · ligand · chains A
- NA · Sodium ion · metal · 2 copies · chains A
- BOG · octyl beta-D-glucopyranoside · additive · 6 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 627 | 0.72 | 0.79 | 50 | BOG |
| 2 | 102 | 0.48 | 0.80 | 18 | empty |
| 3 | 76 | 0.42 | 0.78 | 13 | empty |
| 4 | 78 | 0.35 | 0.75 | 11 | empty |
Compared structures
- 3F48 · Crystal structure of LeuT bound to L-alanine and sodium · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O67854
- Elsewhere: RCSB PDB 3F48 · PDBe 3F48 · UniProt O67854
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.