MolNFT v1 · #6322 · protein

Urokinase plasminogen activator B chain-uki-1D complex

1F92 · Urokinase-type plasminogen activator: “Urokinase plasminogen activator B chain-uki-1D complex”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.42). MolNFT v1 #6322 on GenesisL1: 3D structure, binding sites and…

PDB: 1F92
Type: protein
Length: 248 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Urokinase-type plasminogen activator
EC: 3.4.21.73
UniProt: P00749
Ligands: SO4
Pockets: 1 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Urokinase-type plasminogen activator (EC 3.4.21.73)	protein	248	10% helix, 37% strand	P00749

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	126	0.42	0.76	18	SO4

Modifications

Observed in the structure: 5 disulfide, 1 modified (disulfide, nonstandard).

Compared structures

1F92 · Urokinase plasminogen activator B chain-uki-1D complex · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00749
Elsewhere: RCSB PDB 1F92 · PDBe 1F92 · UniProt P00749

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