MolNFT v1 · #62753 · protein

High quality structure of cleaved pai-1-stab

3EOX · Plasminogen activator inhibitor 1: “High quality structure of cleaved pai-1-stab”. X-ray diffraction, 1 pocket (best druggability 0.30). MolNFT v1 #62753 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3EOX
Type: protein
Length: 370 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Plasminogen activator inhibitor 1
UniProt: P05121
Pockets: 1 · best druggability 0.30

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Plasminogen activator inhibitor 1	protein	370	30% helix, 35% strand	P05121

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.30	0.76	12	empty

Compared structures

3EOX · High quality structure of cleaved PAI-1-stab · the same entry in another collection · chain A against A, TM-score 1.00
P05121 · AlphaFold monomer V2.0 prediction for plasminogen activator inhibitor 1 (P05121) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P05121
Elsewhere: RCSB PDB 3EOX · PDBe 3EOX · UniProt P05121

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