MolNFT v1 · #62638 · protein
Wesselsbron methyltransferase in complex with sinefungin
3ELD: “Wesselsbron methyltransferase in complex with sinefungin”. X-ray diffraction, 2 ligands (SFG, SO4), 2 pockets (best druggability 0.62). MolNFT v1 #62638 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3ELD
- Type
- protein
- Length
- 277 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Methyltransferase
- EC
- 2.1.1.57
- UniProt
- C8XPB0
- Ligands
- SFG, SO4
- Pockets
- 2 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methyltransferase (EC 2.1.1.57) | protein | 277 | 38% helix, 15% strand | C8XPB0 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 481 | 0.62 | 0.76 | 47 | SFG |
| 2 | 85 | 0.31 | 0.73 | 22 | empty |
Compared structures
- 3ELD · Wesselsbron methyltransferase in complex with Sinefungin · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C8XPB0
- Elsewhere: RCSB PDB 3ELD · PDBe 3ELD · UniProt C8XPB0
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