MolNFT v1 · #61857 · protein
Crystal structure of ectrmb in complex with sah
3DXZ · TRNA (guanine-N(7)-)-methyltransferase: “Crystal structure of ectrmb in complex with sah”. X-ray diffraction, 2 ligands (SAH, SO4), 2 pockets (best druggability 0.41). MolNFT v1 #61857 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3DXZ
- Type
- protein
- Length
- 200 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- TRNA (guanine-N(7)-)-methyltransferase
- EC
- 2.1.1.33
- UniProt
- P0A8I5
- Ligands
- SAH, SO4
- Pockets
- 2 · best druggability 0.41
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | TRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) | protein | 200 | 36% helix, 22% strand | P0A8I5 |
Ligands and binding sites
- SAH · S-adenosyl-L-homocysteine · ligand · chains A
- SO4 · Sulfate ion · ion · chains A
- EDO · 1,2-ethanediol · additive · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 95 | 0.41 | 0.77 | 18 | SAH |
| 2 | 93 | 0.35 | 0.74 | 16 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A8I5
- Elsewhere: RCSB PDB 3DXZ · PDBe 3DXZ · UniProt P0A8I5
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