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UniProt P0A8I5

tRNA (guanine-N(7)-)-methyltransferase (P0A8I5)

tRNA (guanine-N(7)-)-methyltransferase (UniProt P0A8I5), EC 2.1.1.33: 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction…

UniProt
P0A8I5
Protein
tRNA (guanine-N(7)-)-methyltransferase
EC
2.1.1.33
Experimental structures
6
Predicted models
1
Ligands
3
Pockets
8 · 1 record with a druggable one

Structures

7 records of P0A8I5 in the MolNFT archive: 6 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
3DXXCrystal structure of EcTrmBx-ray diffractionA—2 (best 0.37)
3DXXCrystal structure of ectrmbx-ray diffractionA——
3DXYCrystal structure of EcTrmB in complex with SAMx-ray diffractionASO4, SAM1 (best 0.47)
3DXYCrystal structure of ectrmb in complex with SAMx-ray diffractionA——
3DXZCrystal structure of EcTrmB in complex with SAHx-ray diffractionASO4, SAH2 (best 0.41)
3DXZCrystal structure of ectrmb in complex with sahx-ray diffractionA——
P0A8I5AlphaFold monomer V2.0 prediction for tRNA (guanine-N(7)-)-methyltransferase (P0A8I5)predictedA—3 (best 0.67)

Ligands

  • SO4 · Sulfate ion · in 2 records
  • SAH · S-adenosyl-L-homocysteine · in 1 record
  • SAM · S-adenosylmethionine · in 1 record

Experiment against prediction

Elsewhere

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